Lithium is an alkali that is soft and silvery-white metal that is so reactive (it sparkles when it comes in contact with water) that it isn’t found in the natural world. Instead it’s found in mineral compounds as well as in mineral water.
Cosmologists believe in lithium was one of the three elements synthesized during the Big Bang. It’s been there for a while.
We often think of lithium as a treatment for mental disorders such as bipolar disorder and manic depression. The lithium-ion battery inside our phones. It is known to explode at times.
It turns out that the anti-psychotic drug lithium isn’t a drug at all. It’s actually an mineral. It’s part of the group of minerals which include sodium as well as sodium.
As a nootropic, micro-dosing lithium provides some amazing anti-aging benefits. Recent research suggests that low dose lithium can also slow the progress of neurodegenerative diseases such as Alzheimer’s, dementia , and Parkinson’s disease.
The low-dose lithium also aids the process of neurogenesis as well as memory. It also helps in regulating mood.
We’ll look at the regular or daily use of Lithium Orotate as an nootropic and how it can benefit cognition health.
Lithium assists in:
- The balance of mood. Lithium can reduce the mania (extreme extremes of highs or lows) through reducing the sensitivity of the norepinephrine post-synaptic receptor. It also increases the uptake of norepinephrine in synaptosomes. It prevents the release of this chemical transmitter. Lithium enhances the transfer of Vitamin B12 and folate into brain cells. It affects the mood and aggression.
- Growth Factors. Lithium increases the levels of brain-derived neurotrophic factors (BDNF) as well as neurogrowth factor (NGF) neurotrophin-3 (NT3) and their receptors. Additionally, lithium increases the number of stem cells in the brain. All of which are responsible for boosting the neurogenesis and aiding in the healing process from any type of brain injuries.
- Neuroprotection. Lithium boosts brain gray matter, enhances DNA replication in neurogenesis, stops apoptosis, enhances N-acetyl aspartate (NAA) and reduces beta-amyloid production and guards against injury once it is formed. It also chelates aluminum and shields against glutamate-induced toxicity.
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Lithium Orotate Uses: Overview
Lithium is an alkali mineral , and is one of the trace elements that are vital for both human and animal reproductive health as well as general wellness and health.
It was discovered as a chemical element in 1817, the first documented medical usage was in 1871, for the treatment of mania.
However, the use for lithium to treat ailments dates way back to Greek as well as Roman times. People would soak into the alkali springs to treat mental and physical ailments.
Mineral springs to treat ailments since the beginning of time.
Springs located in Douglas County, Georgia was so well-known that people traveled for miles to take a sip of the water.
The Sweet Water hotel, a luxurious 500-room hotel, was inaugurated in 1887. It attracted famous authors as well as businessmen and prominent politicians who came to enjoy the health benefits of the spring. Lithia is the name ” Lithia” originates from the lithium-rich water..
Research from all over all over the world have demonstrated the health advantages from the mineral lithium. A study based on information from 27 Texas counties between 1978 and 1987 revealed that the levels for murder, suicide, and the rape rate were higher for counties where drinking water had little or none lithium.
Another study on the lithium concentrations in water from taps from 18 cities in Japan revealed the standard mortality rates lower in areas that had higher levels of lithium.
Another study that was conducted by researchers in Texas during 2013 has confirmed findings of the first study in the state. Water samples taken from 226 counties revealed an relationship between the levels of lithium as well as suicide rate.
Researchers who carried out meta-analyses of the lithium levels and public drinking water have suggested ” increasing lithium levels in drinking water may lower the risk of suicide and also justify the addition of lithium in drinking water from the tap.”
A piece published in The Lancet published in the year 1949 published by John Cade is credited for the use of modern medicine for lithium as a successful treatment for manic psychosis.
The United States FDA approved high doses of lithium carbonate and lithium citrate in the year 1970 for the treatment of bipolar disorder. Carbonic acid and citric acid are minerals that transport lithium throughout your body.
Doctors may also recommend lithium off-label to treat seizures, migraines, and psychosis, usually when other treatments have been unsuccessful.
However, as we dig into the latest research regarding lithium and lithium, we see that the importance of this element vital to ensure the brain’s health and function.
It is believed that the lithium that we obtain from our diets can help prevent many mental and neurological disorders. Micro-dosing lithium for an nootropic using a supplement such as Lithium Orotate could aid in making up things we can’t get from food and water.
Lithium is found naturally in processed meat, fish dairy products, milk eggs, potatoes, and other vegetables. The typical daily consumption from lithium could range between 2 and 600 mg. The amount varies based on the location the food is produced.
Lithium Orotate Benefits
Lithium aids in the brain’s function and health in a variety of ways. Two of them are notable.
- Lithium improves mood. Recent studies have revealed the fact that lithium’s effects on mood stability could result from its capacity to increase the production of new neurons in the brain (neurogenesis).
Lithium blocks the enzyme glycogen synthase Kinase-3b (GSK-3b). This inhibition increases the brain-derived neurotrophic factor (BDNF) and insulin-like growth factor-1 (IGF-1) which stimulates neural stem cells to create new neurons within the hippocampus.
The moment neural stem cells create new neurons within the hippocampus and affect the mood as well as memory function as intended. However, a failure of neurogenesis causes mood disorders.
Lithium has been used for a long time to reduce the symptoms of mania and to stabilize moods for bipolar sufferers. However, it is not commonly considered to be an antidepressant. Researchers from Tel Aviv provided the first evidence that blocking GSK-3b resulted in an quick antidepressant effect on mouse.
Another group at the Howard Hughes Medical Institute in Pennsylvania demonstrated the feeding of mice with chow with low dose lithium for 15 days resulted in an dosing-dependent effect on antidepressants.
Lithium stimulated genes in amygdala, hippocampus as well as the hypothalamus. The entire brain is implicated in depression anxiety, bipolar disorder as well as the autism spectrum and schizophrenia..
- Lithium is a brain protector. The brain cells are constantly at danger of being damaged due to the toxins that you come across daily from water, air, food and the environment. The excitotoxins created by normal metabolism of brain cells.
Glutamate plays an important role in synaptic plasticity that is required to learn and memory. However, excessive activity of glutamate’s NMDA receptors triggers neuron death , which is linked to Alzheimer’s Parkinson’s, Huntington’s and other forms of. Lithium blocks this overactivity.
The lithium also boosts levels of neuroprotective proteins known as BCL-2. Researchers believe the fact that lithium may be the sole “medication” which has proven to boost bcl-2 levels in a variety of brain regions.
Lithium is also being studied in the prevention and treatment of traumatizing brain injuries. In a research study that was conducted in 2014 the researcher the researcher Dr. Peter Leeds stated that lithium had “demonstrated significant beneficial effects in the laboratory models of TBI.” (TBI). This includes a decrease in brain lesions caused by TBI and neuroinflammation suppression and protection from blood-brain barrier disruption and normalization of behavioral impairments and improvements in memory and learning and memory, among others.”
In 1985 the year 1985, in 1985, the United States EPA determined that the consumption of lithium from food items in the USA varied between 0.6 to 3.1 mg/day. To compare, those living within the Andes in Northern Argentina consume 2 to 30 mg a day and 2 to 3 mg in drinking waters.
When your intake of salt as well as caffeine intake increases as will the excretion of lithium in your urine, which raises the need for this vital trace mineral.
Stress and toxins from substances such as mercury, aspartame MSG, Bisphenol A (BPA) and other excitotoxins also increase cortisol levels and various stress-related hormones. This increases your need for water-soluble nutrients , such as B-vitamins zinc, magnesium and lithium.
Low levels of lithium levels are linked to …
- Depression and anxiety increase
- Memory and learning capacity decrease
- Insomnia increases
- Sensitivity to stress and chronic pain increases
- Natural healing processes decline
A regular consumption of lithium can help to prevent many neurological and mental illnesses because of its trace mineral impacts on the metabolism of the nervous system. It also has antioxidant and anti-inflammatory effects.
Lithium’s benefits
The research and clinical studies regarding the neuroprotective properties from lithium are overwhelming that some scientists are starting to wonder ” why isn’t everyone taking lithium“?
Here’s a brief overview of the ways that micro-dosing lithium with lithium Orotate will benefit the brain.
- Blocks the process of apoptosis The molecule lithium blocks GSK-3 that has been associated with the death of cells that are apoptotic.
- NMDA-receptors – Lithium reduces the toxicity of glutamate that is caused by NMDA receptors, which aids in the treatment of mood disorders, Alzheimer’s and various other autoimmune and inflammatory disorders.
- Neuroprotection Blocks the growth of plaque and beta-amyloid tangles
- Neurogenesis – Lithium promotes the BDNF required for synaptic plasticity in memory and learning. Lithium also increases the growth of nerves as well as the glial-derived neurotrophic factor that affects mood, memory, learning and general health of the brain.
- Stem cells of the neuron stem cells of the brain lithium stimulates the stem cells required to create the new neuron (neurogenesis)
- stabilizes the mood Stabilizes mood lithium is known to provide an uplifting effect for healthy individuals as well as those suffering from bipolar disorder, depression, and mania.
- Prevention of suicide sufficient levels of lithium have been proven to decrease the risk of suicide in numerous studies conducted around the world.
- Depression Depression lithium aids in treating resistant depression. In actual fact, lithium has been proven to increase the efficacy of antidepressant drugs.
- N-acetyl Aspartate (NAA) – lithium boosts NAA, which has been linked to higher scores in IQ (i.e. lithium can make you more intelligent!)
Benefits of supplementing your diet with lithium extend beyond improving your cognitive health. Lithium can also help reduce insulin resistance, aids in the treating alcoholism and other addictions, helps support bone health, regulates the cycle of circadian and much more.
Lithium Orotate Anxiety / ADHD / Sleep and More
Some people report feeling the effects after taking a small dosage of lithium rapidly. However, for certain people individuals, the full effects could take anywhere from one to three weeks. Micro-dosing 5-10 milligrams of lithium every day will yield consistent results in a month or two months for certain. I’ve seen amazing results in just only a few days.
If you’re prone to lash out at people with anger and aren’t sure the reason you’re so angry It could be because the fact that your lithium levels are low.
A lot of neurohackers suffering from anxiety and depression notice changes rapidly. Within the first few days, you will feel more relaxed, calm, and feel less stressed..
Be aware the fact that lithium in any form isn’t for everyone. If you’re able to get enough lithium through your water and diet, but still have the mood swings discussed in this article it is possible that you are having other issues. It is possible to determine within a few hours after taking low-dose lithium whether this is the right supplement suitable for you.
For certain people, Lithium Orotate is feeling elated over life, for the very first time in a long while. Stress as well as anxieties about social interaction have become less of a concern. It is now more enjoyable and relaxing.
Some believe that Lithium Orotate is more effective than any other medication has ever been tried to treat depression that is severe. It offers a pleasant and smooth mood balance, without the toxicity that comes with massive doses in lithium carbonate.
If you’re suffering from the symptoms of PTSD or even mild insomnia, you might want to consider the Lithium Orotate. Concentration may increase, racing thoughts lessen and motivation levels may rise. You’ll be able to have greater ability to cope.