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National Lab Day

National Lab Day

Scientific Reviews Made Simple

Michael Walwalsh

Lion’s Mane Supplement: Benefits, Studies and Dosage

May 14, 2022 by Michael Walwalsh

The Lion’s Mane Mushroom is well-known for its ability to stimulate Nerve Growth Factor, which improves memory and cognition, as well as helping to reduce depression.

The Lion’s Mane (Hericium Erinaceus) is unique within the family of mushrooms both in appearance and purpose. The Lion’s Mane Mushroom is highly effective in activating the Nerve Growth Factor (NGF) in the brain.

It is known for its potent effects as an “brain stimulant”, Lion’s Mane is believed to have been utilized in teas for thousands decades in the practice of Buddhist monks. It is believed to boost brain power and improve their ability to concentrate when they meditate. The Lion’s Mane is a nootropic, is a potent stimulant for the regeneration of brain cells aiding in improving the memory as well as cognitive abilities.. The main active compounds found in the Lion’s Mane include hericenones and erinacines. Erinacines aid in the production of greater amounts of nerve growth factor. Erinacines effortlessly traverse over the brain-blood barrier to increase your brain’s production neuronal cells. Lion’s Mane can help:

  • Nerve Growth Factor. The Lion’s Mane Mushroom helps to prevent and treat brain damage caused by nerves. After crossing the blood-brain barrier the Lion’s Mane mushroom stimulates the production of enzymes that releases the growth hormone Nerve Factor (NGF). Regeneration of the nervous system helps alleviate the symptoms of neurodegenerative diseases like Alzheimer’s, dementia and Parkinson’s Disease.
  • Neurogenesis. The lion’s Mane helps in the creation and repair of neurons. It boosts the neurotransmitters and signaling, which affects memory, recall, recall, and mood.
  • Brain Optimization. Lion’s Mane can help eliminate the fog in your brain. It helps to restore mental alertness and memory. It also helps reduce depression and anxiety symptoms.

Table of Contents

  • Lion’s Mane Supplement
  • What is the way Lion’s Mane work in the brain?
  • Lion’s Mane benefits
  • What does Lion’s Mane feel??
  • Lion’s Mane Studies
    • Lion’s Mane Prevents Cognitive Dysfunction
    • Lion’s Mane Induces Nerve Growth Factor
    • Lion’s Mane dosage for Neuropathy
  • Lion’s Mane Dosage
  • Lion’s Mane Side Effects
  • Where to buy Lion’s Mane Mushroom

Lion’s Mane Supplement

Lion’s Mane (Hericium erinaceus) is a medicinal mushroom that has been proven to boost brain the immune system and nerves. In contrast to other mushrooms with caps and stems, Lion’s Mane is a long flowing white tendrils. It resembles a lion’s mane. Some other names are the Monkey’s head, bearded tooth, Pom Pom Blanc, Hedgehog Mushroom and Satyr’s Beard.

The Lion’s Mane mushroom (Hericium Erinaceus) The fungus is parasitic and grows from trees and logs. It is found in North American, Europe and Southeast Asia. In Japan it’s known as Yamabushitake also known as “those who rest in the mountains”. In reference to the Shugendo sect of monks who are hermits, and their flowing, long robes.

As an nootropic the odor of Lion’s Mane has been proven to be especially efficient for stimulating Nerve Growth Factor (NGF) in the brain. NGF is created in the hippocampus throughout the course of life. It regulates the cholinergic receptors and neuroplasticity.

It is also essential to learn. Neuron Growth Factor are specialized proteins that help to regenerate neurons.. Lion’s Mane contains two unique types that comprise NGF’s that are hericenones and erinacines that easily traverse the blood-brain barrier.. Lion’s Mane as well as many other mushrooms that are used for medicinal purposes, has significant amounts of antioxidant beta-glucoxylan as well as four polysaccharides and polypeptides. It has a major impact in boosting the immune system. and reducing the growth of tumors. Lion’s Mane has also been examined in the reduction of amyloid plaques. These clusters made of beta-amyloid protein hinder communication between neurons. They are also implicated in the development of Alzheimer’s disease and other neurodegenerative disorders. Lions’ Mane can also be used to help treat Lyme’s Disease and digestive tract problems. We’re discussing the Lion’s Mane Mushroom and its impact on the health of the brain and chemical balance.

What is the way Lion’s Mane work in the brain?

The lion’s Mane improves the health of your brain and improves its function in a variety of ways. Two are notable.

  1. The Lion’s Mane Mushroom enhances production of Nerve Growth Factor (NGF). It is an amino acid which is a key factor in the survival, maintenance as well as regeneration neurons..

The NGF hormone is needed by the brain to ensure that neurons are healthy and strong. If you suffer from neurological disorders the brain is not able to create its own NGF source internally. In a research conducted at Kuala Lumpur in 2013, researchers discovered the Lion’s Mane extract induced NGF synthesizing and stimulated neurite outgrowth.

  1. The Lion’s Mane is efficient in reducing anxiety and depression. Many even refer to it as”the ” smart mushroom” because of its capacity to boost cognition and memory, as well as work as an antidepressant.

Researchers from Japan conducted with 30 women. Female subjects were suffering from depression, menopausal symptoms sleep quality, and many other issues. The participants received either Cookies laced with Lion’s Mane or a placebo for four weeks. Researchers discovered that Lion’s Mane ” has the possibility to decrease anxiety and depression and suggest a different mechanism than the NGF-boosting action of H. Erinaceus”.

Scientists used to believe that the brain couldn’t develop the new cells in its brain. Once our brains developed in childhood, and when we were adults we were able to have every brain cell that we’d ever need. We know that neurons are able to regenerate.

However, that doesn’t mean they are immune to it. Will regenerate. Numerous health conditions can cause neurodegeneration.  Decrease in Nerve Growth Factor = Decline in Long-Term Potentiation, which affects long-term memory Brain cells die and they aren’t replaced | Neuroplasticity declines resulting in poor memory | Neurotransmitters decrease, causing depression, mood disorders, and depression All of these changes that come with age contribute to neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease and more. As well as depression, anxiety and mood disorders can impact the quality of life.

Lion’s Mane benefits

A minimum of 12 peer-reviewed study have appeared about Lion’s Mane benefits to brain health since 1991. Dr. Kawagishi from Japan was the first to recognize Nerve Growth Factor properties in Lion’s Mane Mushroom. In a double-blind placebo-controlled study, researchers from Japan conducted research with 50 to 80-year-old men and women. All were suffering from mild cognitive impairment. The subjects in the trial received four 250 mg tablets that contained 96 percent of Yamabushitake (Lion’s Mane) dry powder three every daily over a period of 16 weeks. Both genders were examined at 4-8 12, as well as 16 weeks. In each of the test times, those who took Lion’s Mane demonstrated an substantial improvement their cognitive scores. Their scores were growing when they were taking Lion’s Mane supplementation. However, four weeks after stopping the Lion’s Mane supplementation the cognitive scores of their patients decreased dramatically. Researchers found they concluded that the Lion’s Mane Mushroom can be effective in reducing the cognitive function of people with mild impairments.

What does Lion’s Mane feel??

It is possible that you won’t experience the benefits of supplementing by taking Lion’s Mane Mushroom immediately. However, many people report regular usage from Lion’s Mane, a boost in mood and mental energy.  There are reports that it is increasing. Depth Perception . It also provides an improvement in the sense of smell . Others have reported improved decision-makingabilities, the ability to tackle problems and learn. Most likely due to the Lion’s Mane ability to enhance the neuroplasticity. The general consensus is the Lion’s Mane Mushroom’s capacity to reduce anxiety and depression, as well as decrease depression and increase focus.

Lion’s Mane Studies

The Lion’s Mane Mushroom is used as a food item and herbal medicine since the beginning of time throughout East Asia. It has been proven in research conducted by scientists to show that Lion’s Mane promotes Nerve Growth Factor both in petri dishes and also in human and animal test subjects.

Lion’s Mane Prevents Cognitive Dysfunction

This study scientists studied the effects of The Lion’s Mane in amyloid b(25-35) protein-induced memory and learning deficits in mice. Amyloid b(25-35) is a peptide that is associated with diseases such as Alzheimer’s. Mice were injected with peptide between days 7 and 14 of the study. They were also fed a diet that contained Lion’s Mane for 23 days of the study. The results revealed the fact that L’s Mane stopped short-term and memory loss in visual recognition typically caused through amyloid b(25-35) the peptide. They concluded that the Lion’s Mane Mushroom ” may help in the prevention from cognitive impairment”.

Lion’s Mane Induces Nerve Growth Factor

In this study mice were fed Lion’s Mane 5% of freeze-dried powdered extract for seven days. Researchers observed an increase in the levels of Nerve Growth Factor (NGF) in the hippocampus of the mice. The conclusion is that the The Lion’s Mane ” contains active substances that increase NGF synthesizing”.

Lion’s Mane dosage for Neuropathy

In this study conducted with rodents, Lion’s Mane extract was capable of promoting neuron regeneration following injury. Rats suffering from gluteal nerve injury were capable of walking after drinking water containing the Lion’s Mane extract. Researchers concluded that the Lion’s Mane is able to regenerate injured nerve cells. In this instance the change was so significant, the rats were able to go from completely disabled to walking once again.

Lion’s Mane Dosage

Are you unsure of how much Lion’s Mane you should take? The dosage of Lion’s Mane Mushroom is contingent on the quality of the extract. For the extract of Lion’s Mane 10:1 (30 percent polysaccharide), daily dosage is between 500 and 1,000 mg, taken one to three times a each day. That means that if you decide to take the daily dose of 1,000 milligrams of the Lion’s Mane extract it is recommended to consume at least 500 mg before breakfast, and then another 500 mg at noon. The dosage for other extracts sold at retail stores from Lion’s Mane ranges from 300 mg to 3000 mg, taken three times a each day. Look up the label and find out the dosage recommended by the manufacturer. When you first start using the supplement, begin with the lowest dosage and observe how your body responds.

Lion’s Mane Side Effects

The Lion’s Mane Mushroom is not toxic and is considered to be very safe. Therefore, there are very little side effects that have been reported. Certain neurohackers experience itchy skin after high doses. It could be due to an increase of Nerve growth Factor. The lion’s Mane has been studied in animals and showed no adverse effects or toxicity, even as low as 5 grams per kilogram.

Where to buy Lion’s Mane Mushroom

The Lion’s Mane mushroom (Hericium Erinaceus) as a nootropic supplement is typically sold in the form of an extract. It is available in powdered form or as a capsule.    Lion’s Mane Mushroom are available in a few of the best quality pre-formulated nootropic stacks .

When it comes to choosing the best Lion’s Mane supplement, there’s disagreement over the most effective method of extraction that will yield the full benefits of the herb. Many believe that the best choice is to use hot water for extraction. Another suggests alcohol extraction is the best option. Another says both are required. However, when it comes to mushrooms, claiming the one’s “more powerful” than the other is too simplistic to be accurate. This is just as much an art form as the science behind it. It is even more crucial to select an supplement that contains an element of the mycelium of Lion’s Mane Mushroom.

The fruiting body is not a source of the chemical erinacines, which is the one which boosts Nerve Growth Factor (NGF). The nootropic properties from hericenones are only found in the body that produces fruit or the top of the mushroom can help boost your immune system and help get free from Amyloid b(25-35) the peptide that is linked to diseases such as Alzheimer’s. The problem is to find the Lion’s Mane Mushroom extract that has all the spectrum of both the mycelium as well as the fruiting body. However, the mushroom has to grow in liquid, and not on a solid substrate, like grain. Otherwise , you’ll end up with a smashed grain with no erinacines required for the growth of NGF. Check out the literature of the manufacturer and marketing materials and discover the ways in which their Lion’s Mane is cultivated. Also, read reviews on the shopping websites and forums. There are several types of Lion’s Mane available:

  • The Plain Lion’s Hair: Pure, powdered mushrooms. Most often, it is dried in a freeze. It is the most affordable form of it that is available. It can be added to juice, water or smoothies.
  • Extracts of Lion’s Mane: A stronger version of the mushroom. They are often sold as extracts 14:1 or 10:1 (14 tons (or 10 pounds adjusted to one pounds in extract).
  • Standardized Lion’s Mane processed to give precise levels of the active ingredient. It is possible to purchase Lion’s Mane standardized to 30 percent and 50% polysaccharides (including the active secondary metabolites hericenones and erinacines).
  • The Lion’s Mane tea As it’s an extremely well-known mushroom within the home, the flavor is palatable. However, it’s difficult to determine the amount of active ingredient you’re receiving.
  • Amycenone(r)/PLM-Fraction: This “branded” product is standardized to Hericenones 0.5%, Amyloban 6%. It seems to target a lesser-known Lion’s Mane active ingredient-Amyloban-which is positioned as a mushroom compound that fights beta-amyloid proteins. It was developed in Japan and is extremely expensive and can be included in a supplement called Amyloban(r)3399.

If you do decide to choose your own, prior to eating any wild mushroom, be sure it’s identified. The danger of poisoning by mushrooms is a serious issue if you choose an incorrect one.

Filed Under: Nootropics

Phenylethylamine: Foods, Effects Dosage and More

November 17, 2021 by Michael Walwalsh

Phenylethylamine improves working memory executive function, creativity flow, stress reduction more positive mood, anxiety reduction and reduces symptoms of ADHD The effects of ADHD are less severe with

Phenylethylamine (PEA 2-phenylethylamine (b-phenylethylamine Phenethylamine,) is a trace amino acid. The brain naturally transforms the amino acid L-Phenylalanine to Phenylethylamine (PEA).

PEA isn’t among the top Nootropics stack options due to its effects being so brief-lived. However, some neurohackers love PEA because of it’s stimulantand mood-enhancing properties.

The most well-known promoter of Phenylethylamine is the Dr. Alexander Shulgin and his wife Anna. The Dr. Shulgin published ‘ PiHKAL: An Chemical Love Story’ in the year 1991. PiHKAL stands to mean ” Phenethylamines I Have known and loved”.

Phenylethylamines are a class of Phenethylamine derivatives that contain PEA as the backbone. The derivative compounds are created through the replacement of hydrogen molecules within the structure of the core.

This category comprised of PEA substances includes amphetamines, stimulants, empathogens, psychoactives, appetite suppressants, nasal decongestants, bronchodilators and antidepressants.

One of the more famous PEA derivatives is Methylenedioxymethamphetamine (MDMA or Ecstasy).

The Dr. Shulgin developed, tested and published formulas for 179 compounds that are largely based on PEA’s structure. PEA in his book PiHKAL.

In this review, we examine the way the phenylethylamine (PEA) works in the brain.

Phenylethylamine Effects

Phenylethylamine aids:

  • Anxiety & Depression. PEA stimulates TAAR1 as well as TAAR2 receptors, which then hinders the absorption and increases production of ‘feel good neurotransmitters dopamine and serotonin.
  • Neuroprotector. Monoamine Oxase blocks the catecholamines such as dopamine and norepinephrine. Dopamine levels decrease and are linked to diseases such as Parkinson’s disease. PEA aids in increasing dopamine as well as norepinephrine levels. Reduces the symptoms of neurodegenerative diseases.
  • Attention Deficit Disorder (ADHD). PEA blocks the reuptake of norepinephrine and dopamine, and hinders their transportation. Similar to its mechanism of action espoused through ADHD stimulants medications. Certain have reported that supplementing by using PEA in the form of a nootropic has reduced ADHD symptoms. ADHD.

Table of Contents

  • Phenylethylamine Effects
  • Phenylethylamine Foods
  • Phenylethylamine Brain
  • Phenylethylamine’s Benefits
  • Phenylethylamine Foods
    • Phenylethlamine in Chocolate
  • Phenylethylamine Effects
    • Phenylethylamine Weight Loss
  • Phenylethylamine Clinical Research
    • Phenylethylamine as an Antidepressant
    • Phenylethylamine ADHD
  • Phenylethylamine Dosage
  • Phenylethylamine Side Effects
  • Where to buy Phenylethylamine

Phenylethylamine Foods

Phenylethylamine (PEA 2-phenylethylamine (b-phenylethylamine Phenethylamine,)is a trace natural amine that is synthesized by the L-phenylalanine within your brain.

Aromatic amino-acid decarboxylase transforms phenylalanine into the phenylethylamine. It is also the enzyme that transforms phenylalanine to dopamine. It converts it at a rate that is comparable to the production of dopamine.

However, PEA isn’t stored within the neuronal vesicles as dopamine is stored. In contrast, monoamine oxidase-B (MAO-B)quickly degrades PEA.

Despite its brief time-to-effect, PEA as a nootropic appears to be effective in stimulating catecholamine activity through the stimulation of dopamine as well as norepinephrine.

PEA is found naturally in a variety of cacao algae, fungi and bacteria, and clover beans, peas, as well as certain food items like Natto and eggs.

PEA can also be found also in chocolate which is made in the cocao’s roasting and fermentation processes.

PEA is a receptor for C-proteins, TAAR1 and TAAR2 which are receptors that are reserved to traceamine use. The receptors mentioned above are not utilized by other neurotransmitters of major importance, such as norepinephrine or dopamine.

Half-life for PEA used as an Nootropic Supplement is between 5 and 10-minutes. Because it is quickly destroyed by monoamine oxidase B (MAO-B).

A lot of neurohackers elucidate the negative effects of PEA through the use of an monoamine oxidase B inhibitor ( MAOI) such as selegiline (L-deprenyl) or hordenine and Oat Straw.

Phenylethylamine Brain

Phenylethylamine improves brain health and function in a variety of ways. Two of them are notable.

  1. Phenylethylamine decreases depression. PEA naturally increases the ‘feel good neurotransmitters dopamine as well as serotonin in your brain. Research has shown that depression sufferers, when tested, are less likely to have levels of PEA.

Some even studies suggest that there is a PEA deficit could be the reason for depression in the beginning. In one study, 14 patients suffering from severe depression consume up to 60 mg a each day Phenylethylamine (PEA) together with the dosage of 10 mg selegiline (L-Deprenyl) for up to 50 weeks.

Researchers discovered that “PEA provides long-lasting relief from depression in a large amount of patients, with those who are not responsive to conventional treatment. PEA boosts mood just as quickly as amphetamine, but it does not create tolerance.”

  1. Phenylethylamine can be described as an mesencephalic enhancer. PEA is regarded as to be a mesencephalic enhancement that is described by ” enhancer-sensitive neurons in the brain that can work for a brief period of time at a high level of activity because of endogenous enhancer chemicals”.

This implies that PEA triggers the release of norepinephrine, dopamine and serotonin from the brain. However, unlike stimulant drugs such as amphetamine that release a surge of neurotransmitters in an uncontrolled way;

PEA does not increases the amount of neurotransmitters released when a nerve is stimulated when it receives an signal from a nearby neuron.

Also, the pattern of the release of neurotransmitters has unchanged. However, when a neuron is able to normally release a neurotransmitter more than the normal amount of it is release.

The result is almost immediate improvements of cognition and the ability to pay attention, be aware and pleasure, libido and a feeling of well-being.

Phenylethylamine is an endogenous (natural or built-in) amphetamine. This is the mechanism that determines the way prescribed ADHD stimulants such as Adderall perform. And the basis for many Schedule 1 drugs like MDMA, LSD, mescaline, and (crystal) methylamphetamine.

Phenylethylamine (PEA) can be metabolized naturally by monoamine oxidase B (MAO-B). As we age MAO-B levels increase and reduce healthy amounts of PEA.

Low PEA levels have been associated with a variety of neurological disorders. It can cause:

  • Higher likelihood of ADHD
  • Higher likelihood of addiction
  • Energy levels decline
  • Working memory and mood decline
  • Contributing to Parkinson’s Disease

However the presence of high levels of PEA is linked to schizophrenia and migraines.

Phenylethylamine’s Benefits

Phenylethylamine (PEA) quickly crosses the blood-brain barrier when you consume it. You feel the effects immediately.

Activation of TAAR1 receptors stop the uptake and triggers the release of dopamine, norepinephrine and serotonin. It’s like increasing the amount of activity in neurons.

A higher level of neurotransmitters can increase the feeling of pleasure and motivation, enhances the memory and cognitive abilities, and increases the ability to control impulses.

PEA naturally regulates and maintains neuronal activity. It prevents over- or under-stimulation. When it is working according to the plan, PEA and other trace amines can prevent metabolic dysfunction and neurological disorders.

As a neurotransmitter, PEA behaves like it looks and behaves like amphetamines. It also produces the same effects that are normally that are associated with the use of the stimulant. However, unlike amphetamines and because PEA is a natural substance that can be found in the brain, adverse reactions and tolerance are largely avoided.

PEA is a brain part of the brain that is associated with emotion. This results in feelings of joy as well as increased energy and impulse control enhanced creativity, as well as improved sense of smell.

PEA increases libido, social behavior, a feeling of well-being, and improves overall performance.

PEA is being researched and is being used to treat of ADHD and depression, as well as bipolar disorder and cognitive impairment such as the fog of brain and low focus. Furthermore, PEA is promising in treating eating disorders and addictions.

Phenylethylamine Foods

Phenylethylamine is a type of drug which releases dopamine in your brain. This food can be used to create this drug in small amounts but the effects only last for 10 minutes.

Phenylethylamine is a natural chemical that is responsible for pleasurable feelings. It is also responsible for the “love drug” effect that people experience when they are in love with someone.

Phenylethylamine is found in chocolate, strawberries, bananas, avocados, red wine and green tea. With these foods you can prepare delicious meals that make you happy!

Phenylethylamine is a natural chemical that causes excitement and elation.

Phenylethylamine is a natural chemical found in the human body. It causes an “adrenaline kick” or excitement and elation.

Phenylethlamine in Chocolate

The foods that contain phenylethylamine are usually spicy, salty or contain chocolate.

Phenylethylamine Effects

PEA can be quickly degraded by monoamine oxidase B (MAO) so unless you combine PEA with an MAO inhibitor do not expect its effects to last for long. The majority of people experience peak energy within 15 minutes, and then lasting energy for 30 minutes. up to an hour.

If you’re ADHD or ADD You should notice improvements in your mood and attention span concentration as well as mental clarity. It’s not quite the same result that you’d experience from Adderall but with the added benefit of a greater social connection.

Neurohackers recommend using the MAOI (inhibitor) supplement 15 minutes prior to the PEA dose. The effects will last for about two hours. There’s not a crash as that you would normally get from an stimulant. It’s just a general feeling of wellbeing after it has worn off.

A few have said that PEA has helped to break off the addiction to the drug Phenibut as well as caffeine without experiencing withdrawal.

As a pre-workout aid, PEA provides a more intensive and focused exercise.

Neurohackers who are older seem to experience greater benefit from PEA. It is likely because the monoamine oxidase levels are higher than dopamine as older you become. Furthermore, using PEA particularly with a MAOI aids in restoring dopamine and other neurotransmitters which are commonly diminished as you age.

PEA is an excellent nootropic to study as you will experience less stress, fewer anxiety attacks, and less anxiety. Plus, you will experience more positive mood, it’s more focused and have more energy.

Phenylethylamine Weight Loss

Certain people report that their cravings for food decrease and it’s much easier to lose weight.

Phenylethylamine Clinical Research

Phenylethylamine as an Antidepressant

Depression ranks as the 2 2nd most common reason for disability in the ages of 15-44. In 2030, it is predicted that by 2030, the World Health Organization predicts depression to be the most significant reason for disability in the world.

Selective serotonin Reuptake inhibitors (SSRI) are the most commonly prescribed antidepressants worldwide. SSRIs are effective by blocking the serotonin transporter , and thereby preventing the process of reuptake of serotonin. This results in an increase in serotonin levels in synapses.

However, the SSRIs take a long time to work. They also come with a myriad of adverse negative effects. Phenylethylamine (PEA) may be an alternative to SSRIs.

A study conducted in 2008 revealed that PEA affects serotonin transporters through interactions with receptors for TAAR. The increase in serotonin levels is due to the inhibition of their reuptake, just like the prescription SSRIs.

The study suggests that PEA could be a better treatment for depression as compared to SSRIs.

Phenylethylamine ADHD

Diagnosis of ADHD is traditionally been determined by analyzing symptoms. However, the measurement of PEA levels has now been suggested as a biomarker to diagnose ADHD.

The discovery of a connection with PEA concentrations and ADHD has enthused researchers. It is because it could improve levels of confidence in ADHD diagnosis. It will also reduce the risk of misdiagnosis and over-medication.

One study found that ADHD children treated with the drug methylphenidate (Ritalin) showed significantly higher PEA levels in the presence of the drug methylphenidate.

PEA is a binding agent for the TAAR1 receptor, which modifies the monoamine transporter function. It also causes the reduction of the reuptake process of serotonin, dopamine, and norepinephrine. This increases the amount of these neurotransmitters within synapses between neurons.

The increase in synaptic concentrations of dopamine is achieved through blocking directly the transporter of dopamine. This is the way that drugs such as the methylphenidate help to increase dopamine levels.

If you’re ADHD and you crave chocolate It’s probably due to the fact that the cocao is a source of PEA.

Certain naturopaths are starting to prescribe PEA in lieu of stimulants such as amphetamines and the methylphenidate for treating ADHD.

Phenylethylamine Dosage

Phenylethylamine (PEA) The recommended dosage for cognitive benefits is 500 mg, up to 3 times per day.

PEA has an estimated half-life of 5 to 10-minutes. However, PEA’s effects PEA can be prolonged by making use of a MAO-B inhibitor.

If you decide to use an effective MAOI such as selegiline (l-deprenyl) ensure that you limit the dosage to a minimum (i.e. 2.5 mg) or you’re at risk of reducing MAO-A’s effectiveness. More details on”the ” cheese effect” in the next section.

Doing more than is the recommended amount is not a good option because you’ll probably be irritable, feel anxious and possibly even suffer from headaches, experience nausea, and likely increase your heart rate to alarming levels.

Phenylethylamine Side Effects

“Cheese effect“: Phenylethylamine (PEA) is processed through an enzyme called MAO-B. When Monoamine Oxase (MAO) is blocked through eating cheese, or any other medication or natural MAO inhibitor (MAOI) in combination, it could result in a risky increase of blood pressure.

Research has shown the fact that the selective MAO-B inhibitory is not responsible for the cheese-like effect. The cheese effect is not a result of selective MAO-B inhibition.

Some examples of MAO-B inhibitors that are selective include selegiline at low doses (L-deprenyl) and hordenine. Oat Straw, Glycyrrhiza uralensis (Chinese extract of licorice), Phellondendron amurense (Amur cork tree bark), Ferula assafoetida extract (resin), as well as Psoralea corylifolia (Bu Gu Zhi). [xx*

Do not take Phenylethylamine (PEA) if you are taking an approved MAOI such as Marplan, Nardil, Azilect or Parnate or have taken one within the last 14 days.

Don’t use PEA If you suffer from Phenylketonuria (PKU).

A lot of PEA could cause irritability, nausea, increased the heartbeat, and jitteriness, and can be very dangerous.

Keep in mind that Phenylethylamine (PEA) is an endogenous (natural) amphetamine. If used in a reckless manner, it can cause the same harmful adverse effects as other substances in the amphetamine class of compounds.

Where to buy Phenylethylamine

Phenylethylamine (PEA) is available in tablets, capsules, and also as a bulk powder.

Do not make the error of purchasing Phenylalanine in place of Phenylethylamine (PEA). It’s not the same thing. It’s easy to overlook in the search on the internet for this nootropic.

Filed Under: Nootropics

Piracetam: Use, Review, Dosage Guide

November 17, 2021 by Michael Walwalsh

Piracetam has been proven to improve Cerebral Circulation enhance creativity, increase the fluency of speech, improve memory, recall and learning and boost mood

Piracetam (2-oxo-1-pyrrolidine-acetamide, Nootropil) is a water-soluble ampakine nootropic in the racetam-class of compounds. Piracetam was synthesized for the first time by Dr. Corneliu Giurgea, a Belgian pharmacist firm UCB Pharma in the 1964.

Piracetam is regarded as the first nootropic that has been created. A cyclic derivative of GABA, Piracetam was initially designed to be a calming form of medication for motion sickness. However, despite its relationship with GABA Piracetam did not exhibit any of the behaviors that was correlated with the tranquilizing nerve transmitter. It is also not able to directly affect GABA receptors.

Giurgea discovered that Piracetam could boost cognitive function regardless of health individuals. The company introduced this drug as ‘Nootropil within Europe in the 1970’s early. The popularity of Nootropil quickly allowed UCB Pharma to expand its operations, which resulted in the development of many new pharmaceutical products. The Dr. Giurgea coined the term “nootropic” to refer to the cognition-enhancing compounds.

Nootropic is derived from the Greek words meaning “mind” (noos) as well as “towards” (tropein). Piracetam is available as a prescribed drug ( Nootropil and Lucetam) in Europe. It is also sold in South America, Piracetam is available under the brand name Noostan (Argentina), Breinox (Venezuela and Ecuador) and Nootropil (Mexico). Piracetam is also sold under the names Lucetam, Oikamid, Smart, Geratam, Biotropil, Neurobasal, Stimulan and Nocetan across the globe. The United States, Piracetam is available in the United States as an OTC supplement under the names Piracetam as well as Nootropil.

A myriad of racetam derivatives have been created based on Piracetam. Racetams, like all synthetic compounds have the same nucleus of pyrrolidone. Piracetam affects AMPA receptors and enhances the activity of Acetylcholine within the brain. A popular racetam in those in the community of nootropics. Neurohackers utilize Piracetam to improve the memory as well as the ability to learn.. If you’re planning to begin exploring racetams I suggest that you do so during National Lab Day is to begin with Piracetam. Because it’s effective well, it’s secure and less expensive than the other racetams in the racetam family. Piracetam helps:

  • inflammation: Piracetam is a powerful analgesic (anti-pain). The analgesic effects are related to the inhibition of inflammatory markers such as the IL-1b. and the prevention of decreased glutathione ferric reducing capability as well as free radical elimination
  • neurotransmitters: Piracetam potentiates the flow of, and enhances the effects of Acetylcholine (ACh) within the brain. Studies have demonstrated that it can significantly enhance memory and learning.
  • The Cerebral blood flow: Piracetam improves blood flow to the brain. A better flow of blood provides more nutrients and oxygen to brain cells, enhancing the ability to focus, memory, and cognition.

Table of Contents

  • Piracetam Review
  • Piracetam Dosage Guide
  • Piracetam Use
  • Piracetam 800mg Uses
  • Piracetam Side Effects
    • Piracetam Improves Cognition
    • Piracetam Enhances ATP Production
  • Dosage of Piracetam that is recommended

Piracetam Review

Piracetam (2-oxo-1-pyrrolidine-acetamide, Nootropil) was the first in the racetam-family of nootropic compounds. It is a non-water-soluble ampakine nootropic. AMPA (a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic) refers to one of three glutamate receptors in your brain.  Piracetam It was developed by a colleague of the famous Russian scientist Ivan Pavlov, Dr. Corneliu Giurgea was the first to synthesize Piracetam in the Belgian pharmaceutical company UCB Pharma in the 1964. After the discovery of Piracetam numerous nootropics have been developed within the racetam class of substances.

They all share an nucleus of pyrrolidone at the core. Piracetam is an cyclic derivative of GABA.. However it doesn’t alter GABA receptors within the brain. In fact, Piracetam was found to regulate AMPA as well as NMDA receptors, and enhance the performance of the neurotransmitter Acetylcholine (ACh). AMPA as well as NMDA receptors, along with Acetylcholine is associated with the development of learning as well as memories. When Piracetam is combined with an Choline supplement, its effects are more prominent. Researchers have demonstrated in a multitude of studies in clinical trials that piracetam greatly improves memory and learning. Piracetam can also increase the flow of cerebral blood.

Blood supplies glucose and oxygen required for cell metabolism and also helps in the elimination of cell waste. Vital for the highly-optimized brain. Piracetam is available as a prescription medication in many nations around the globe. The United States, Piracetam is available in the form of an unregulated OTC study drug.

Piracetam Dosage Guide

Piracetam improves brain health and function in a variety of ways. Two of them are notable.

  1. Piracetam affects AMPA as well as NMDA receptors in the brain. It also improves the flow of Acetylcholine (ACh) and sensitivity and the density of ACh receptors.

This German study, conducted using mice in the lab showed that Piracetam increased NMDA receptors. It also normalized the way these receptors functioned in conjunction with L-Glutamate like that of healthy brains. Deficits in the levels of NMDA receptors may represent one of the causes of action that underlie the decline in cognitive function that occurs with age.

The researchers concluded that Piracetam demonstrated cognition-enhancing properties. The effect of this of NMDA receptor sites is directly connected to our desire to use Piracetam to enhance Long-Term Potentiation as well as the enhancement for the long-term memory development. Neuroplasticity depends on the activation of NMDA receptors. This neuroplasticity is at the core of memory creation. The reviews of Piracetam, a drug that neurohackers use frequently mention the reemergence of memories that were lost for a long time. Another evidence of the effectiveness of using Piracetam to aid in memory and learning.

  1. Piracetam boosts the flow of cerebral blood. Numerous studies have demonstrated how Piracetam can positively influence the flow of blood in the brain. The flow of blood in the brain is crucial to the brain’s highly efficient. Blood supplies glucose and oxygen required for cell metabolism and assists in the elimination of the cellular debris.

Strokes may be caused by the interruption of cerebral blood flow. The brain is deprived of glucose and oxygen. The double-blind, placebo-controlled research was conducted on 24 patients suffering from stroke. One group was given 2,400 mg of Piracetam two times every day, while the other group received was given a placebo.

Prior to treatment the two groups performed similarly in their performance on the language task. The study revealed that Piracetam helped in the recovery of many language functions. This effect was attributed to increased blood flow to brain regions that are related to language. The group that was a placebo showed minimal improvement in areas related to the language.

As we age the brain’s metabolism and chemistry change. It seems that these changes are impacting younger and younger individuals.

  • Recall Reaction time, learning capacity decreases
  • ATP energy levels decline Density of AMPA as well as NMDA receptors decreases.
  • Acetylcholine levels decline Cerebral blood flow declines

These changes are all the main causes of cognitive decline. The first signs of these changes are evident in slow decision-making, learning difficulties or recalling basic things such as an important appointment. Even if you’re not worried about age-related signs Piracetam may be able to aid.

Piracetam Use

Piracetam aids in increasing the flow of blood to the brain, increases the levels of oxygen, increases the use of glucose in brain cells, and helps maintain the brain cells mitochondria and ATP and ATP.

Piracetam can also be a powerful stimulator of AMPA sensitive glutamate receptors in neurons. It enhances the number of binding sites that are specific to AMPA within neurons synapses.

Glutamate can be described as the main excitatory neurotransmitter found in the brain. The glutamate activity of Piracetam influences the ability to focus, alertness as well as memory and learning. One of the reasons that neurohackers regularly affirm that Piracetam enhances memory and mental performance. Piracetam boosts the uptake of high-affinity choline (HACU) which is the process that takes place in the nerve endings of cholinergic nerves. It also facilitates the acetylcholine (ACh) formation.

The stimulation of ACh by piracetam has an impressive impact on memory and learning. Piracetam can also increase the density of choline receptors in the brain’s frontal cortex. The area of your brain used for working memory and decision-making.

The ATP energy is vital for the survival of your brain. Brain cells have to produce the majority of ATP by consuming oxygen and glucose. The brain’s energy metabolism of carbohydrate is dependent upon the flow of cerebral blood, oxygen uptake and glucose.

Piracetam increases the utilization of glucose and also increases ATP production required to fuel brain cell mitochondria. And Piracetam is a drug that has analgesic (anti-pain) advantages. The anti-pain effect is linked with the Piracetam’s anti-inflammatory properties.

Inflammation can trigger pain and research has shown that Piracetam has a profound impact on pain. Piracetam increases acetylcholine, so it is recommended to add a source of choline. Consider Alpha GPC or CDP-Choline which contain Piracetam. Give your brain all the choline it requires.

Piracetam 800mg Uses

The majority of neurohackers experience a significant improvement from Piracetam within two weeks. Take into consideration that Piracetam affects the brain’s chemical. This change is not likely to take place in a short time. The brain requires time to get used to the change in the acetylcholine (ACh) concentrations and the way it utilizes it. The increased cerebral blood flow takes some time to increase the levels of nutrients and oxygen.

Also, for your neurons to react. The mileage you get could differ according to the neurochemical composition of your brain. Many recommend starting with an attack dose for the first 3 days. A 3,000 mg “attack dose’ of Piracetam for instance to begin with theoretically helps to get more of the supplement into your system straight immediately. It will take less time to build up before you begin experiencing the effects. Then, you can lower to a minimum dose and increase the dosage until you have found your personal ideal dosage.

When you start to feel how you feel after taking Piracetam you’ll likely experience an increase in increase in mood and less anxiety around social situations and increased creativity, as well as improved speaking fluency and improved memory. Piracetam can increase the brain’s ability to use Acetylcholine. Therefore, you’ll likely discover that adding a source of choline (Alpha GPC or CDP-Choline) to your Piracetam stack can help.

Piracetam Side Effects

There is plenty of evidence to support Piracetam improves memory in humans and animals who suffer from various kinds of cognitive impairment in humans and animals. Be aware that the majority of the research that is available for nootropics has been conducted with patients who are sick and trying to recover. The ROI of research conducted at universities and institutions is derived from the treatment of diseases.

It is not about helping everyday biohackers, like us, to gain an edge at school or at work. However, we can extrapolate the results of these studies to discover whether and how something like Piracetam helps our cognition and memory. Every now and then, someone takes some time and conduct such an investigation on healthy individuals. Similar to this study conducted with healthy, normal volunteers. Researchers provided this healthy group of participants four capsules of 400 mg of Piracetam three times a day (4,800 mg in total) over 14 consecutive days. The effects on memory were not noticed after 7 days of the study. However, within 14 days, verbal learning was significantly improved.

Piracetam Improves Cognition

Researchers from Belgium (where Piracetam originated) performed an study of 19 placebo-controlled, double-blind studies conducted on patients with cognitive impairment or dementia and who were taking Piracetam. This meta-analysis showed the differences between those who took Piracetam or an alternative. The final result of this study provided convincing evidence of the effectiveness of Piracetam in a variety of groups of cognitively impaired people.

A number of studies and user reviews have proven that Piracetam dosage can make a difference. In contrast to other nootropics that start with a lower dosage and gradually increase and up, with Piracetam starting with a higher recommended dosage. The study conducted in Germany using 78 patients who were elderly found significant differences in the improvement of cognition when taking Piracetam with 1,600 mg three times daily. The study found not a difference between cognitive performance when patients received 800 mg three times daily. Dosage is important when taking Piracetam.

Piracetam Enhances ATP Production

Piracetam is utilized all over all over the world to treat cognitive impairments due to brain injury, aging as well as dementia and Alzheimer’s Disease. Numerous studies have shown that Piracetam improves the production of ATP, mitochondrial membranes and neurite growth in neurons.

In this study, researchers examined how Piracetam in relation to mitochondrial function. Brain cells from humans were treated using Piracetam in normal conditions as well as under conditions that mimic the aging process and damage caused through ROS ( reactive oxygen species). Also, with cells that represent the early stage of Alzheimer’s Disease. The Alzheimer’s disease-related cells had impaired mitochondrial function under the conditions of baseline. Piracetam could reverse the cells’ mitochondrial dysfunction and restore mitochondrial function to normal. Researchers have demonstrated that Piracetam can restore mitochondria in people suffering from mild Alzheimer’s disease and restore the function of cells back in a regular.

Dosage of Piracetam that is recommended

The recommended Piracetam dose is 1600 mg three times daily. A single Piracetam dosage in the early morning and one in the afternoon, and another in the afternoon.  It is likely that you will want to begin with an ‘attack dose’ when first beginning using Piracetam.

Filed Under: Nootropics

Aniracetam: Review, VS Piracetam, How to take and more

November 17, 2021 by Michael Walwalsh

Aniracetam is known to reduce depression, improve memory and learning, increase the flow of your speech, enhance enjoyment of music, and increase your social interaction.

Aniracetam (1-p-anisoyl-2-pyrrolidinone) is a fat-soluble ampakine nootropic in the racetam-class of compounds. Aniracetam can be 10 times more potent than the first racetam, piracetam.. Aniracetam was first patented by the Swiss pharmaceutical firm F. Hoffmann-La Roche AG in the 1978.

It has a structure similar to Piracetam. Aniracetam is, as with all racetam nootropics, contains an Pyrolidone Nucleus at the heart of it. Aniracetam is available as a prescription medication ( Ampamet, Draganon, Memodrin, Referan, Sarpul) in Europe. It is also sold as an ingredient within the United States. A popular racetam in those who are part of the community for nootropics. Neurohackers utilize Aniracetam to improve memory and improve learning. It also helps to ease anxiety and depression, stress and increase social sociability.

Aniracetam helps:

  • Optimizing the Brain Aniracetam dramatically enhances brain function following traumatic brain injury, including stroke (ischemia). It also increases your brain’s capacity to heal injured cell membranes.
  • Neurotransmitters: Aniracetam reduces the desensitization of glutamate (AMPA) receptors in your brain. This enhances neural signaling by increasing the efficiency of glutamate. This results in improved concentration as well as focus.
  • Brain Energies: Aniracetam improves memory and recall. It produces 200-300 percent more Acetylcholine within the brain. This can improve focus and the clarity of thinking.

Table of Contents

  • Aniracetam Review
  • Anairacetam vs Piracetam
  • How to take Aniracetam Powder?
  • Aniracetam High Benefits
  • Is Aniracetam legal?
  • Aniracetam vs Piracetam
    • Aniracetam Depression
    • Aniracetam Memory
    • Aniracetam Fetal Alcohol Syndrome
  • Aniracetam Dosing
  • Aniracetam Side Effects
  • Where to Buy Aniracetam
  • Aniracetam Dosage

Aniracetam Review

Aniracetam is part of the racetam-family of compounds that are nootropic. It is an oil-soluble ampakine nootropic. AMPA (a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic) refers to one of three glutamate receptors in your brain.

It is believed that the class of racetam of nootropics has an the pyrrolidone nucleus at the heart of their. Additionally, Aniracetam is an chocorergic substance, which means it alters the acetylcholine concentrations in brain. Aniracetam is available as a prescription medication in Europe and a few parts in Asia with the following names: Ampamet, Draganon, Memodrin, Referan, and Sarpul. It is available as an over-the-counter, non-restricted substance within the United States.

However, it is it is not sold as a nutritional supplement. One of the first synthetic nootropic substances It is referred to as an cognition booster. It is also known as having anxiolytic, as well as anxiety-reducing effect. Aniracetam is believed to be 10 times more powerful as Piracetam. As a nootropic ampakine, it improves the amount of attention span, alertness and improves memory. Ampakines are known to produce an stimulating effect. However, they do not cause the similar stimulant adverse effects as Ritalin or coffee after prolonged usage.

Anairacetam vs Piracetam

The Swiss-based pharmaceutical company F. Hoffmann-La Roche AG developed Aniracetam in the late 1970’s, as an alternative to Piracetam. Aniracetam is fat-soluble, whereas Piracetam is water-soluble. Fat-soluble molecules can cross over the brain-blood barriers more quickly than water-soluble molecules. Aniracetam is more effective in the brain following having it, than Piracetam because of its higher biological availability for the brain. However, its effects do not last for as long as Piracetam.  The power of Aniracetam is almost unintuitive. Since the majority of the Aniracetam dose is absorbed by the liver as it is digested. It is only 0.2 percent or the initial dose is accessible for the brain.

Piracetam is almost 100 percent bioavailable. The two Aniracetam as well as Piracetam both are cognitive stimulants. Both possess neuroprotective properties. Both racetams can enhance the ability to learn as well as memory. Both are able in helping repair damage to the brain. Aniracetam offers additional benefits that are that are not available with Piracetam. Aniracetam is able to reduce anxiety, depression, and fear. It also improves sociability. This could be a sign of the effects it has on dopamine as well as serotonin receptors within the brain.

How to take Aniracetam Powder?

Aniracetam improves brain health and function in a variety of ways. Two of them are notable.

  1. Aniracetam affects AMPA receptors in the brain. The principal metabolite of Aniracetam (70-80 percent) is N-anisoyl GABA and is the one responsible for many of its effects.

2-Pyrrolidinone and P-anisilic acid are other metabolites of the drug (20-30 percent) Both of them are also actively. The primary purpose of these metabolites lies in their effect on the glutamate system within the brain. It decreases the desensitization to glutamate receptors. This triggers glutamate to be able to function as a neurotransmitter glutamate to be more readily available to the brain. Greater glutamate levels mean more cognitive ability as well as memories. Also, the protection of neural cells and repair after brain injuries.

  1. Aniracetam may also affect dopamine and serotonin receptors in the brain. This can lead to better levels of mood and social sociability.

A study published within the European Journal of Pharmacology demonstrated the anti-anxiety properties of aniracetam. Researchers studied the brain pathways of mice, demonstrating Aniracetam’s mechanisms in effect illustrating the effects on serotonin and dopamine.

Glutamate is an excitatory cousin of GABA, which is an excitatory relative of. While GABA is calming it also is a stimulant. Glutamate is by far the most commonly used neurotransmitter found in the nervous system central. However, glutamate is harmful for brain cells.

In excess, it in the brain could kill brain cells. Lou Gehrig’s Disease for instance is caused by excessive glutamate. However, glutamate is a key neurotransmitter that is found in the brain. It connects brain circuits that are involved in memory, learning , and perception. Too much glutamate can cause neurode death.

  • Too little glutamate can create issues in memory, learning, and perception
  • Acetylcholine levels decline
  • These changes can occur at any time

They are the result of what we consume, the drinks we drink, our lifestyle and our air quality, and more.  It is believed that Aniracetam could help with cognitive decline due to age, and also for students who wants to perform better at school. Through boosting acetylcholine levels and regulating glutamate levels in the brain.

Aniracetam High Benefits

Aniracetam regulates AMPA receptors that are involved in the way glutamate is utilized in the brain. A greater amount of the neurotransmitter glutamate is in the brain. This means that there is better neural communication over the synapses. Your brain is functioning at its peak regardless of fatigue, stress and anxiety.

There is evidence from anecdotal sources that Aniracetam improves the communication between right and left brain hemispheres. You are more imaginative. You are more likely to make creative and innovative choices. Aniracetam when combined with choline increases manufacturing of the vital neurotransmitter Acetylcholine.

Enhancing memory, recall and concentration. Aniracetam is fat-soluble and rapidly gets into your brain once you have taken it. Once it is in your brain, it increases the transmission of signals and also helps protect neurons. Aniracetam increases acetylcholine levels, so it is recommended to add a source of choline. Consider the Alpha GPC or CDP-Choline that contain Aniracetam. Give your brain all the choline it requires.

Is Aniracetam legal?

Nootropics users report:

  • Aniracetam to tool for studying. As a stand-alone supplement, Aniracetam seems to increase the attention span of many neurohackers. When combined by caffeine have reported working effortlessly for long periods of time.
  •  The auditory sense is enhanced . If you are a music lover Aniracetam will take you further into the experience of listening. Small details such as background guitars and other audio effects are brought to life. Every instrument is part of the stage.
  • Greater visual clarity. Visual effects from Aniracetam make you feel as if your brain processing a wider range of what’s within your visual field. The natural world and the surroundings appear more vivid and stunning.
  • Sociability. Many people report having the ability to express thoughts and have improved speaking skills. Your vocabulary and language seem to flow easily. Ideas and thoughts flow without effort.

It is likely that you will feel the effects of aniracetam within a few hours of taking it. It’s fat-soluble, so it is digested and absorbed into your cells rapidly. A dose of 750 mg of Aniracetam is expected to last for a few hours. In contrast to the other stimulants there isn’t a “crash” after Aniracetam is out of your system.

Aniracetam vs Piracetam

Researchers studied 276 patients suffering from cognitive disorders. They received Aniracetam and examined at 3 months, six and 12 months. Better emotional states and improved motor function was seen within three months.

An increase in cognitive performance was noticed after 6 months. The findings were concluded Aniracetam ” is a potential treatment option for those suffering from cognition deficit” problems. The improvements lasted throughout the 12 month study. There was also a positive impact on the emotional stability of people suffering from dementia.

Aniracetam Depression

An article that was published in Psychopharmacology in 2001 revealed that Aniracetam was able to stimulate dopamine release. The study identified Aniracetam as being effective against depression that is caused by the brain’s dysfunction caused by age.

Aniracetam Memory

Researchers have put mice and rats through six different scenarios. From memory loss caused by drugs to avoiding electric shocks when they administered Aniracetam. The outcomes of all tests proved Aniracetam increasing cognitive performance. It didn’t matter what tests they did to these animals. Memory and learning improved through the use of Aniracetam.

Aniracetam Fetal Alcohol Syndrome

We’re exposed to toxic substances everywhere we travel. In everything we do throughout the day. The exposure to toxins causes destruction in our bodies and brain, which includes. In this study, researchers discovered a way to repair the damage to synaptic transmission within the brain. The study exposed pregnant Sprague-Dawley rats to ethanol as well as an artificial sweetener that resembles saccharin.

The pups born to these female rats are typically exceptionally cognitively  impaired. Like children born to mothers who drink. In this study, puppies born with fetal alcohol condition were treated using an antidepressant drug Aniracetam between at a time between 18 and 27 days following the birth. Aniracetam completely restored synaptic connections within their brains. It also reversed any cognitive impairments that are associated with the fetal alcohol syndrome.

Aniracetam Dosing

The recommended Aniracetam dose is 1500 mg daily. Taken in two 750 mg doses. A single Aniracetam dosage in the early morning, and another in the late afternoon. A dose of 750 mg of Aniracetam that is taken in the morning can last until noon. A noon dose of 750 mg of Aniracetam will last until mid-afternoon.

Aniracetam can be available in capsule, tablet and powder forms. Tablets and capsules typically contain 500 mg each. Because aniracetam is an fat-soluble nootropic that you can take in conjunction with a healthy meal that contains fats. You can also take it with a tablespoon of unrefined coconut oil, or extra olive oil that is virgin.

Aniracetam Side Effects

Aniracetam is not toxic. It is therefore considered to be well-tolerated and secure. The effects of side effects are not common but may include fatigue, anxiety headaches, nervousness, and nausea. These side effects are usually due to excessive doses of the nootropic. Headaches caused by Aniracetam usually occur when you don’t take it along with a Choline supplement. Headaches can be a sign of a deficiency in choline in the brain.

Where to Buy Aniracetam

Aniracetam is available in capsule, tablet and powder forms. Tablets and capsules typically contain 500 mg each. The most reliable place to purchase Aniracetam in powder or capsule in powder form can be found at HR Supplements based in Phoenix, AZ. HR Supplements has been operating for more than 25 years and has a large testing lab, and their products are of the highest quality. I’ve used their products and would recommend them. In Europe as well as other nations around the globe, Aniracetam is a prescription medication. It is sold by the brands Ampamet, Draganon, Memodrin, Referan, and Sarpul.

Aniracetam Dosage

Aniracetam 1,500 mg per day  I would recommend taking Aniracetam as an nootropic supplement. The body doesn’t produce Aniracetam by itself. To reap its benefits, you need to use it as an supplement. Aniracetam is particularly beneficial for people suffering from depression. Research has shown that it can help to reverse and stop the signs and symptoms of depression. It is a no-no

Filed Under: Nootropics

Tyrosine: Foods, Benefits, Depression and More

November 15, 2021 by Michael Walwalsh

Tyrosine improves executive function, working memory and creative flow states. improved mood, stress reduction and anxiety reduction, as well as lessens the symptoms of ADHD The effects of

L-Tyrosine is the master precursor that is required to make the majority of catcholamine neurotransmitters. The brain utilizes the enzyme called tyrosine hydroxylase to transform L-Tyrosine into the L-DOPA. The decarboxylation process of L-DOPA leads to the synthesis of neurotransmitter dopamine. Once converted into dopamine, the enzyme dopamine-beta-hydroxylase converts L-DOPA into norepinephrine (noradrenaline). And Phenylethanolamine N-methyltransferase converts norepinephrine to the hormone epinephrine (adrenaline). The neurotransmitters in this triad are collectively referred to by the term ” catecholamines”. Tyrosine can be a highly effective nootropic for boosting cognitive function. It is especially helpful to maintain cognitive performance under any stress. This includes music that is played at or above 90 decibels. L-Tyrosine functions in synergy in synergy stimulants such as methylphenidate (i.e. Ritalin).

Drugs such as Ritalin are effective in blocking the process of reuptake of the neurotransmitters norepinephrine and dopamine. If there’s not enough dopamine to perform what it’s supposed to, Ritalin isn’t working very effectively. L-Tyrosine can trigger the production of dopamine in extracellular cells.. L-Tyrosine can also increase T3 and 4 production. like T 3 (triiodothyronine) and T 4 (thyroxine) which are essential to maintaining general physical and cognitive health. L-Tyrosine may boost libido, concentration, memory, focus and mood. It also has antidepressant effects and enhances executive functioning in people with ADHD. Tyrosine assists in:

  • Cognitive Stress. L-Tyrosine is the catalyst for the catecholamine-triad of neurotransmitters dopamine, norepinephrine, and epinephrine. Stressors that cause sleep deprivation or extreme such as cold and heat can reduce catecholamine levels. L-Tyrosine replenishes them and helps preserve the highest levels of cognitive function.
  • Neurotransmitters. L-Tyrosine is the primary precursor to dopamine, norepinephrine and epinephrine. When your levels of dopamine increase it makes you more able to focus and organize your thoughts and remain productive.
  • Attention Deficit Disorder (ADHD). L-Tyrosine is beneficial as an efficient treatment option for ADHDsymptoms. It functions in conjunction with other pharmaceutical medications such as Ritalin and Adderall by increasing the levels of extracellular of dopamine. Making these drugs more efficient. As well as reducing side effects such as crashes after the drug is worn off.

Table of Contents

  • Overview: L-Tyrosine Changed My Life?
  • L-Tyrosine vs N-Acetyl L-Tyrosine (NALT): What’s the Difference?
  • L-Tyrosine Foods within the Brain?
  • L-Tyrosine benefits
  • L-Tyrosine Depression
  • L-Tyrosine Foods
    • L-Tyrosine is a treatment for ADHD
    • L-Tyrosine reduces blood pressure under stress
    • L-Tyrosine increases cognitive flexibility

Overview: L-Tyrosine Changed My Life?

The brain converts L-Tyrosine into L-DOPA, which produces dopamine, a neurotransmitter. Dopamine that is not used up is transformed into neurons that produce norepinephrine (noradrenaline) as well as the epinephrine (adrenaline). The triad of neurotransmitters is collectively known as ” catecholamines”.

“Tyrosine” is an abbreviation of the Greek word Tyros , meaning cheese. The first time it was discovered was by German scientist Justus of Liebig, in the year 1846, in the casein protein from cheese. Tyrosine is regarded as a non-essential amino acid since it is synthesized by your body by the phenylalanine. It is present in a variety of high protein foods like fish, poultry, dairy and soy products, as well as nuts such as lima beans, avocados, and bananas.

L-Tyrosine improves executive and working memory within the brain’s prefrontal cortex. It aids in creative flow states, and is a source of creativity, mental flexibility, and also the type that of “convergent thinking” that you can do during multiple choice tests. L-Tyrosine aids with the creation of thyroid hormones T 3 (triiodothyronine) and T 4 (thyroxine) which are essential to maintaining general physical and cognitive health.

L-Tyrosine vs N-Acetyl L-Tyrosine (NALT): What’s the Difference?

N-Acetyl-L-Tyrosine (NALT)is the amino acid L-Tyrosine with an acetyl-group added. If you take NALT in the form of a supplement, it is broken down by the kidneys and is converted back to L-Tyrosine. In theory both supplements provide the same benefits. There is a debate within the nootropics community about what is more efficient. is NALT as well as simple L-Tyrosine. NALT is a less soluble version of L-Tyrosine, so it will become more accessible to the body. Some studies have shown that in certain instances there is a significant percentage of NALT supplemental is eliminated through urine prior to its conversion to the L-Tyrosine. Personally I’ve had no problems using NALT to get a dose for L-Tyrosine.

It provides me with a dopamine boost and adrenal stimulation that you’d think of when supplementing with the dopamine precursor. However, if I don’t have any NALT, I can change to L-Tyrosine, but at a higher dose. When dealing with ADHD/ADD, L-Tyrosine is particularly effective when stacked with ALCAR (Acetyl-L-Carnitine).

ALCAR is able to cross over the brain-blood barrier to boost the acetylcholine concentrations. It also appears to influence positively serotonin levels. Additionally, Tyrosine gives my brain the dopamine that it requires to reduce the symptoms associated with ADHD/ADD. I have found that stacking L-Tyrosine together with 20mg of Ritalin every day is particularly effective. It is evident that the brain isn’t able to make enough dopamine on it’s own. It also requires the boost from the addition of Tyrosine. So like all nootropics, YMMV. Be aware of the way each nootropic functions together with other nootropics within the collection. Also, how they interact with any medication you have to take. This is as much an art like science. It is also crucial to experiment for the best cognitive performance.

L-Tyrosine Foods within the Brain?

L-Tyrosine improves brain function and health in a variety of ways. Two of them are notable.

  1. L-Tyrosine enhances memory and cognition in the face of stressful conditions.. Acute stress refers to temporary stressors that affect the ability to think. Examples include extreme cold or heat. Examples include cold showers, extreme automobile accidents, sports relationships and intense films and business deals that go awry exam results and war zones.

In a study conducted by the University of Bedfordshire in the UK The effect on the effects of the amino acid L-Tyrosine in cognitive function was assessed prior to the exercise test. Researchers recruited eight soccer players. They then had them take an hour-long soccer simulation test in an environment chamber that was set to 77 degrees Fahrenheit. The soccer players received either L-Tyrosine prior to exercise or placebo.

Cognitive performance was assessed prior to the exercise task. It was then measured again at “half-time” after half-time, and then following the entire exercise. The cognitive performance test assessed the dual-task as well as vigilance. The results showed that the cognitive vigilance as well as reaction time of football players greatly improved after the administration of L-Tyrosine. The results showed that under warm weather circumstances, L-Tyrosine could enhance cognitive function and reduce cognitive impairment when exposed to heat stress from exercise.

  1. L-Tyrosine increases neurotransmitters. L-Tyrosine, when taken as a supplement transforms to the brain’s neurotransmitter dopamine. Dopamine is a neurotransmitter that controls the movement of your body. It is essential to memory and attention, as well as problem solving.

Dopamine that is not used can transform into neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). Norepinephrine is essential for attentiveness emotional state, sleep, dreaming , and learning. Epinephrine drives your ‘flight-or-flight’ response.

This is what triggers your response to danger in emergency situations or when you’re in stressful situations or situations. In a study conducted in the Netherlands researchers examined whether L-Tyrosine could boost the cognitive capacity that are associated with cognitive control. They conducted tests to test ” working memory” by using an N-Back test.

Participants in the study were asked to take part in an “1-back” situation of moderate difficulty, and then a 2-back situation of more difficult level of difficulty. The ones who used L-Tyrosine showed superior performance on the 2-back test, however not in the 1-back test. The study’s authors concluded that L-Tyrosine can provide greater cognitive improvement as cognitive demands increase. The conclusion is that the supplementation of L-Tyrosine could aid you to improve the IQ score due in order to increase the amount of catecholamine you have.

As we age our body and brain change in chemistry and energy metabolism.  Dopaminergic neurons are damaged or die.

  • Neurotransmitter levels decline
  • Thyroid hormones decline
  • Stress levels increase
  • The decline in mood and working memory

These changes are usually blamed on the process of aging. However, they could also be the result of lifestyle and diet choices. If not checked, they can cause neurodegenerative illnesses such as Parkinson’s disease, a decline in quality of life, and depression.

L-Tyrosine benefits

L-Tyrosine may increase levels of the neurotransmitters dopamine and norepinephrine, as well as the hormone epinephrine. It also aids in producing the thyroid hormones T 4 and T3.

Tyrosine helps to increase cognition particularly when you are in stressful circumstances. It aids in improving decision-making flow state, the ability to think creatively, as well as cognitive flexibility and working memory.

L-Tyrosine converts into L-DOPA to produce dopamine. L-DOPA can also be utilized to create melanin within the body. This process aids in the elimination from neurotoxic chemicals known as quinones. It also chelates heavy metals such as lead and mercury that can build up and cause damage to neurons.

The dopamine not utilized by the brain is used to make norepinephrine (noradrenaline) which is essential for emotional alertness sleep, dreaming, and learning. L-Tyrosine is a potent nootropic when combined together with the ADHD/ADD medications such as Ritalin and Adderall. It assists in supplying extracellular dopamine that is needed to enhance the efficacy of stimulants that increase the absorption of dopamine within your brain.

L-Tyrosine Depression

Remember the fact that the L-Tyrosine can be regarded as a precursor for catecholamines. Therefore, if you’re not “low’ in dopamine, norepinephrine or epinephrine it is possible that you won’t ‘ feel’ any sensations.  A lot of neurohackers have reported a boost in mood, and a better The focus , Concentration Increased energy levels, feeling of overall well-being. L-Tyrosine may help you adjust the level of motivation.

It may help reduce anxiety levels, particularly social anxiety. L-Tyrosine supplementation can lower blood pressure when it is elevated due to stress or a stressful environment. Do it prior to the event that is stressful if you are able to.

L-Tyrosine assists in buffering adverse effects caused by stimulants such as caffeine and amphetamines. It can enhance and prolong effect of Ritalin or Adderall and also reduces the risk of crash. If you’re an athlete or manual work You’ll notice that taking L-Tyrosine prior to an exercise or construction task can leave you feeling fantastic afterward. It can help reduce the negative effects of stress that is caused by stressors of short duration. L-Tyrosine assists the body produce melanin, and you might be able to achieve a more natural an even tan at the beach.

L-Tyrosine Foods

L-Tyrosine is a treatment for ADHD

A number of studies have examined the use of L-Tyrosine to treat ADHD. A study that was that was published in the 1980’s found that L-Tyrosine provided temporary relief from ADHD symptoms. However, the subjects eventually developed the point of tolerance and decreased impact. It is crucial for neurohackers to be aware of. It appears that L-Tyrosine, on by itself can help some more than other people.

No matter if you’re dealing with ADHD or you’re mentally healthy. I’ve read many reports of users who have nootropics who have developed tolerance within one week of supplementation with L-Tyrosine. However, the majority of peer-reviewed and published studies have shown positive results.

A study published in Neuropsychiatric Disorder and Therapy in the year 2011 examined the use of amino acid precursors in treating ADHD. This included L-Tyrosine to treat dopamine and 5-HTP to treat serotonin. The study involved 85 adolescents aged 4-18 years old, all of whom had an official diagnosis of ADHD.

The patients were treated for a first time period of between 8 and 10 weeks. Urinary samples for dopamine and serotonin levels were taken within the first four weeks. If they weren’t able to reach the required levels, the subjects were switched to higher dose levels 2 , and finally 3, until they experienced relief from their symptoms. Researchers discovered that serotonin and dopamine precursors produced similar results to Strattera as well as Ritalin. Furthermore ” the amino acid protocol could be comparable in effectiveness to powerful, pharmaceutical ADHD medication“.

L-Tyrosine reduces blood pressure under stress

This research is especially interesting because of its nootropic use. It is widely accepted that blood pressure increases when we’re stressed. The cause of stress isn’t important. Stress increases blood pressure rising. A study conducted in Amsterdam revealed that the administration of L-Tyrosine reduced blood pressure for about 15 minutes after the ingestion. The study was conducted to assess the performance of a task in response to an acute stress.

Stress that is acute tends to be temporary and may be caused by fighting, driving or athletics, martial arts training and fighting training CrossFit Cold showers and extreme movies, loud music and loud noises.

It can also be caused by relationships, business transactions exam, school and much more. The key point is that this study can be applied to all of us. The study revealed the fact that L-Tyrosine decreased diastolic blood pressure in just 15 minutes after having taken the supplement. The blood pressure returned to normal within one hour. The study suggests that L-Tyrosine can cause the reduction of blood pressure due to stress. It can be used to reduce the negative effects of stressful events when it is taken before to the event that is stressful.

L-Tyrosine increases cognitive flexibility

The term “cognitive flexibility” is a term used to describe those who are able to adjust their thinking speedily to change to new circumstances and situations. A high level of cognitive flexibility is linked with greater flexibility in intelligence, superior reading and comprehension as well as an overall healthy brain. The latest research (2015) confirms the notion that L-Tyrosine improves cognitive flexibility. In this study researchers enlisted 22 adults. They also conducted a double-blind placebo-controlled trial. Each subject was assigned an assignment switch procedure to assess their flexibility. The results indicated that L-Tyrosine supplementation improved cognitive flexibility when compared with the control group. The Researc

Filed Under: Nootropics

Noopept: Dosage, Powder, Side Effects and More

November 12, 2021 by Michael Walwalsh

Noopept is a well-known drug for its ability to boost memory, cognition, learning and perception. It also improves mental clarity and mood

Noopept (n-phenylacetyl-l-prolylglycine ethyl ester or GVS-111) is an ampakine nootropic similar in action to the racetam-class of compounds. Noopept can be 1000 times more potent than the first racetam, piracetam. Noopept was developed by the Russia-based drug company JSC LEKKO Pharmaceuticals in the year 1996.

The research shows that that Noopept is similar to other nootropics however it performs differently from other nootropics within the racetam family. Noopept isn’t considered to be a real ” racetam” since it does not have an 2-oxopyrrolidinecore. Noopept is not present in blood samples when used as an supplement. Instead, it increases the concentrations of the cycloprolylglycine (CPG) in the brain.

CPG is a dipeptide composed of glycine and proline that is a moderator of the transmission of acetylcholine as well as AMPA receptor function. Noopept is licensed in both Russia as well as the USA. It is available as a prescribed drug in Russia as well as other countries which were members of the Soviet Union. It is also sold as an supplements within the United States. Neurohackers utilize the Noopept to improve cognitive ability, memory and learning. They also help improve the ability to perceive, reflexes, thinking, and mood. Noopept assists:

  • Brain Optimizing: Noopept boosts Nerve Growth Factor (NGF) and brain-derived Neurotrophic Factor (BDNF). Essential to the neuroplasticity as well as long-term potentiation. The health of the brain is improved as does the ability to retain long-term memories.
  • neuroprotection: Noopept stops the release of excess glutamate in your brain. Glutamate is the brain’s main excitation nerve transmitter. If there’s a shortage of oxygen within the brain, neuron are unable to take in glutamate. This causes excessive levels of glutamate in brain cells. This can lead to neuron destruction and even death. Reducing the neurotoxic overload the Noopept is a potent protection against neurotoxicity.
  • Neurowaves: The drug Noopept increases Alpha and Beta brainwave activity. You feel calmer and more imaginative. It’s much easier to enter the flowing condition. You are also more likely to make innovative and efficient decision.

Table of Contents

  • Noopept Wikipedia
  • Noopept Vs. Piracetam: What’s the difference?
  • Noopept WebMD: What does it do?
  • Noopept benefits
  • What does Noopept feel??
  • Noopept Powder
    • Noopept Nerve Growth Factor
    • Noopept Brain Waves
    • Noopept Memory
  • Noopept Dosage
  • Noopept Side Effects
  • Noopept for Sale

Noopept Wikipedia

Noopept (n-phenylacetyl-l-prolylglycine ethyl ester or GVS-111) is often included in the racetam-family of nootropic compounds. However, it isn’t a ” racetam” since it doesn’t have an 2O-pyrrolidine nucleus.  Noopept Noopept was created in Russia and is referred to as Noopept or GVS-111. The Russian pharmaceutical firm JSC LEKKO Pharmaceuticalssynthesized Noopept in the year 1996, based on the neuropeptide that is naturally produced Cycloprolylglycine (CPG).

Researchers from Moscow discovered Noopept like Piracetam in its nootropic effects however, it also has anxiolytic activity. Noopept is a water-soluble ampakine nootropic. AMPA (a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic) refers to one of three glutamate receptors in your brain. Noopept can also be thought of as an Cholinergic compound due to its effect on the levels of acetylcholine in the brain.

One of the newest synthetic nootropic substances, Noopept is widely regarded as an cognition booster. It is also well-known as having anxiety-reducing, or anti-anxiety properties. The Noopept is believed to be as high as 1000 times more powerful in comparison to Piracetam. It is it is an ampakine nootropic, it can help improve the amount of attention span, alertness and improves the 3 levels of memory. Memory formation Retention as well as memory formation, retention and. Ampakines are known to produce an stimulating impact. However, they do not cause the same stimulant-like side effects like Ritalin or coffee after prolonged usage.

Noopept Vs. Piracetam: What’s the difference?

Russian-based pharmaceutical company JSC LEKKO Pharmaceuticals created Noopept in late 1996 in the late 1996 as a peptide analog of the nootropic that was originally discovered Piracetam.

The two substances, Noopept as well as Piracetam are both water-soluble. Both both as well as Piracetam both are cognitive stimulants. Both possess neuroprotective and anxiolytic (anti-anxiety) qualities. Both racetams can enhance memory and learning. Both are also able in helping fix brain injuries. However, Noopept offers additional advantages that are not that are shared by Piracetam. The first is that the dose for Noopept in comparison with piracetam is 1,000 times lower.

The typical dosage for Noopept is between 10 and 30 mg, whereas Piracetam is usually dosaged to 3 or 4000 mg. The second reason is that Piracetam assists only in the initial phases in the process of memory. However, Noopept affects the consolidation of memory and retrieval processes too. This Noopept assists you to build your memory, keep the memory and later remember what you’ve saved in your memory. Noopept also has a specific anxiolytic (anti-anxiety) effect. Researchers believe that this is due to Noopept’s antioxidant effects, anti-inflammatory properties, and ability to block the neurotoxic effects of excessive glutamate and calcium.

Noopept WebMD: What does it do?

Noopept improves the health of your brain and improves its functioning in a variety of ways. Two of them are notable.

  1. Noopept regulates AMPA as well as NMDA receptors as well as Acetylcholine (ACh) transmission. Noopept increases the amount of the cycloprolylglycine (CPG) in the brain. CPG is a dipeptide composed of glycine and proline that is a stimulator of the transmission of acetylcholine, as well as AMPA as well as NMDA receptors.

If brain cells are deprived of oxygen, glutamate , which is the brain’s main excitatory neurotransmitter does not perform as efficiently in conjunction with neurons. This can result in an accumulation of glutamate that is toxic in brain cells. This can cause neuron damage and eventually, neuron death.

Noopept modulates neuroreceptor function keeping glutamate transmission at normal levels. It protects brain neurons and other cells from damage caused by glutamate. The Noopept is also proven to regulate the acetylcholine flow within your brain. Restoring harmony between glutamate and Acetylcholine function, not just safeguards your brain from injury. It may also improve cognition and memory, as well as learning mood, and recall. It can also ease anxiety.

  1. Noopept enhances Nerve Growth Factor (NGF) and brain-derived Neurotrophic Factor (BDNF) and mRNA. NGF and BDNF are directly linked with the neuroplasticity. The ability to repair and develop new brain cells could be a major factor. Particularly for those suffering from neurological brain damage such as Parkinson’s disease or Alzheimer’s. Even affecting the Long-Term Potentiation required to develop long-term memory.

mRNA alters gene expression as well as intracellular communication within brain cells. The continuous brain signaling process and the expression of genes within brain cells is essential to maintain good cognitive.

A study that was conducted in Moscow demonstrated that long-term use of Noopept for a long time increased NGF and the BDNF and the mRNA. The animals in the study displayed no evidence or evidence of resistance. Long-term use of Noopept increased the neurotrophic effects.

Glutamate is an excitation-related relative of GABA . While GABA can be calming, glutamate is a stimulant. Glutamate is one of the commonly used neurotransmitter found in the nervous system central.  However, glutamate is toxic to neurons. In excess, the amount in the brain could kill brain cells. Lou Gehrig’s Disease for instance is caused by excessive glutamate. However, glutamate is a key neurotransmitter that is found in the brain.

It connects brain circuits that are involved in memory, learning and perception. Too much glutamate can cause neurode death.

  • Too little glutamate can create issues in memory, learning, and perception
  • Acetylcholine levels decline
  • Nerve Growth Factor declines
  • Brain-Derived Neurotrophic Factor declines These changes can occur at any time.

They are the result of what we eat and drink and lifestyle choices and our air quality, and more. It is believed that Noopept could help with cognitive decline due to age, and also for students who wants to perform better at school. Through boosting NGF, BDNF and acetylcholine and regulating glutamate levels within the brain.

Noopept benefits

Noopept modulates AMPA and NMDA receptors . AMPA receptors is related to how calcium and glutamate are used in the brain. With Noopept It’s more of a neuroprotective function.  Like that of the AMPA receptor Similar to the AMPA receptor, the NMDA receptor is also linked to calcium and glutamate use in the brain.

They both influence the way neurons utilize glutamate. Noopept regulates levels of glutamate in as well as between neuronal cells. It reduces glutamate-induced toxicity and also influences the process of Long-Term Potentiation (LTP). LTP is linked to neuroplasticity which permits memory for long periods of time to develop. There is evidence from clinical studies that Noopept enhances neuron signaling and communication.

Through enhancing Alpha as well as Beta brain waves. You’ll feel calmer and more imaginative. It’s much easier to get into the flow state. You are also more prone to make creative and effective choices. Noopept creates an anxiety-reducing (anti-anxiety) result.

It increases dopamine receptors (D2 and D3) and acetylcholine receptors called nicotinic. Additionally, Noopept is also believed to affect certain serotonin receptors. All of which contribute to a better well-being and decreasing anxiety. Noopept has been demonstrated in the lab to increase the activity of Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). NGF as well as BDNF play a role with neuroplasticity as well as the repair and regeneration damage to brain cells. This results in better overall brain health, cognition and memory. Noopept is water-soluble and rapidly gets into your brain once you have taken it. Once inside your brain, it improves signal transmission and also protects neurons.

What does Noopept feel??

Nootropics users report:

  • Noopept is a tool for studying. In its own way, Noopept increases concentration and concentration for a lot of neurohackers. Mental arithmetic is easier and grasping difficult concepts is much easier.
  • Improved verbal fluency. Your communication skills can improve by using the help of Noopept. Vocabulary becomes more easily. Focusing helps towards a balanced conversation. Neurohackers have reported being more friendly, outgoing and less self-conscious.
  • Better mood. With Noopept, you could be able to handle stress-inducing situations and workplace issues that usually cause you to feel down. After you have gotten over the initial few weeks of painful memories due with PTSD, it is possible that you could feel that your emotions are less overwhelming. It is possible to feel disconnected in a an uplifting way from the painful memories.
  • music appreciation. A lot of users have reported increased enjoyment listening to music making use of the Noopept. Some users find it difficult to take music to a completely different level. The distinction between different instruments in sound tracks is less difficult. In general music is more enjoyable.
  • Memory for long-term duration. Noopept alters BDNF and NGF which can affect the long-term potential. Certain neurohackers have reported memories that were that were long gone suddenly pop up. This could be either positive or negative, I guess dependent upon the memories. However, reports suggest that memories are crystal clear. If they’re not, there’s an emotional disconnect protecting against unpleasant emotions.

It is likely that you will feel its effects Noopept within a few hours of taking it. The drug is insoluble in water and is absorbed into your cells rapidly, especially when you consume it in a sublingual manner. However, a word of caution do not exceed the recommended dosage of 10-30 mg daily dose! There is no additional benefits, and may cause undesirable adverse negative effects. There’s some debate about the water-solubility issue of Noopept. It’s not fat-soluble however it definitely isn’t a bad idea to take high-quality “good fat” in the Noopept dosage.

Noopept Powder

Noopept Nerve Growth Factor

A study released by the Russian Academy of Medical Sciences in Moscow confirms that Noopept increases Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). The study scientists examined the effects of one and long-term treatments (28 days) of Noopept. The results showed that one-time treatment increased the mRNA within the brain cortex of rats. MRNA is a molecule found within brain cells that contains codes that originate from DNA which define the amino acid sequences of proteins. Long-term treatment for Noopept resulted in an increase of the brain-derived Neurotrophic Factor (BDNF). Researchers speculated that this sequence of events within the brain is involved in the regrowth of neurons. Enhancing neurotrophin synthesis within the hippocampus enhances cognitive performance. In particular, it improves memory the ability to consolidate memory and delay retrieval. The team of researchers found the following: the drug Noopept ” holds much potential to stop the progression of Alzheimer’s disease in those with moderate cognitive decline”.

Noopept Brain Waves

Researchers from Moscow examined how the injection of Noopept in rats to determine how it affects the brain’s signals. The research team discovered that Noopept enhanced Alpha and Beta brainwave activity throughout the brain. You will experience the Alpha wave when you are more relaxed. Alpha waves are linked to high-level learning, flow state, and happiness. Beta waves are linked to attention, concentration and cognition. The study found the fact that NMDA receptors were involved in one dose of Noopept. In contrast, AMPA receptors were activated following long-term use in the form of the drug.  NMDA receptors are connected to long-term potentiation (long-term memory) and neuroplasticity. AMPA receptors are associated with an increase in brain activity in signaling. Enhancing cognitive abilities as well as memories.

Noopept Memory

“Noopept” is a well-known component of the community of nootropics for increasing memory. Numerous studies have supported the claim that memory is improved with the Noopept. A study conducted by the Russian Academy of Medical Sciences in Moscow conducted experiments with the drug Noopept for rats. The animals were taught an avoidance-based response.. The ability of the animal to build memories in addition to keep a memory was affected. However, once the rats were given an injection of Noopept the rats were capable of retaining the memory and then retrieve the information later. In the other words, Noopept normalized the capacity to learn in animals that have damaged cerebellum. and improved training capacity in rats that have a genetic learning impairment. The study found the fact that ” Noopept improves all three stages of memory”. It was particularly evident for those with impaired memory. Another study that was conducted with rats , found it was found that Noopept increased learning even after one administration. Repeated treatment actually raised the percentage of learners who were successful for animals who had did not succeed in the beginning instruction.

Noopept Dosage

The recommended dose of the Noopept dosage is between 10 and 30 mg daily. Noopept is extremely bioavailable and can easily cross the blood-brain barrier.

Noopept is available in capsule, tablet, and powder forms. The capsules and tablets are typically at 10 mg per. Noopept is a primarily water-soluble nootropics, but it doesn’t readily dissolve in juice or water. Therefore, it might be helpful when you drink it in conjunction in conjunction with a healthy meal that contains fats. Also, you can take a teaspoon of expeller cold-pressed coconut oil or olive oil. Other healthy fats similar to coconut that will ensure fast absorption. For even quicker absorption you can use Noopept sublingually. Allow the tablet or powder to dissolve under your tongue , so it will go straight into your bloodstream and then into your brain. Bypassing your digestive system completely.

Noopept Side Effects

Noopept is synthetic nootropics and is considered safe. Therefore, it is considered safe and secure. So as long as you adhere to the dosage guidelines.

Rarely, side effects may include headaches, fatigue and insomnia, as well as stomach upset. The majority of side effects are caused by extremely high doses of nootropic. Headaches resulting from taking Noopept are usually caused by the fact that you do not use it in conjunction with a Choline supplement. Headaches can be a sign of a lack of choline in the brain.

Noopept for Sale

Noopept is available in capsule, tablet and powder forms.

The capsules and tablets are typically 10-mg each. In the USA The most convenient option to purchase Noopept in powder or capsule forms is HR Supplements which is located at Phoenix, AZ. The firm has been in operation for more than 25 years, has a vast testing laboratory and their products are of the highest quality. I’ve used their products and would recommend them. In Russia and different Eastern European countries, Noopept is a prescribed drug.

Filed Under: Nootropics

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